Serotype switching in Pseudomonas aeruginosa ST111 enhances adhesion and virulence supporting data and scripts

<div>In this study, we characterize the role of the O-antigen, a fundamental part of the bacterial pathogen <em>Pseudomonas aeruginosa</em>. The O-antigen is a polymer of sugar molecules which extends from the surface of the bacteria and into the environment in which it resides. Here we have devised a method to genetically engineer bacteria to express different types of O-antigen with focus on two specific serotypes: O4 and O12. We proceed to study how this affects the bacteria's ability to adhere to plastics, how it affects specific outer membrane proteins such as the type IV pili, and finally how it affects the bacteria's ability to cause infection.</div> <p>This repository contains the following files:</p> <p>Rawdata.7z<br> Scripts.7z</p> <p>Readme.txt</p> <p>Explanation:<br> Extract both archives to the same folder: move both archives to the same folder and press "Extract here". These have been seperated for license reasons.</p> <p>The archive "Scripts.7z" contains R scripts that have been used to analyze data and some raw data for certain datasets (virulence, twitching motility). The license for this archive is -  © Copyright 2024 Technical University of Denmark BSD-3-Clause</p> <p>The archive "Rawdata.7z" contains any raw data used for the manuscript and is published under - © Copyright 2024 Technical University of Denmark CC BY 4.0 license.</p>